Clinical Evaluation of the NanoDetect-TB Mycobacterium Tuberculosis Detection Kit for the Diagnosis of Tuberculosis Disease

Inclusion Criteria: * Children and adults aged two years or older (including older adults that are 65+) * Ability and willingness to provide informed consent/assent/permission, and a parent/legal guardian willing to give consent on the child's behalf for study participants aged 2-17 years * Ability and willingness to perform study procedures, or parent/legal guardian to provide consent for a child to undergo study procedures on their behalf (when applicable) * Clinical signs and symptoms typically associated with active TB disease including, but not limited to: Cough for \> two (2) weeks Lethargy, weakness, malaise Reduced playfulness (pediatric population) Weight loss or loss of appetite Failure to thrive (pediatric population) Fever Chest pain Night sweats * Physician (or healthcare provider) suspicion of TB disease Exclusion Criteria: * Pregnancy (based on participant-provided information) * Any physical or mental health condition for which participation in the study, as judged by the investigator, could compromise the well-being of the subject and/or prevent, limit, or confound protocol-specified procedures * Critical illness needing immediate medical care * Receipt of treatment for active TB or LTBI in the past 24 months