Cancer immunotherapy has the great potential to achieve long-term survival in patients with a solid malignancy. However, the beneficial effect of cancer immunotherapy is seen in only a minority of patients. Mounting evidence suggests that immunosuppressive features in the tumor microenvironment prevent an effective antitumor defense. The aim of the investigators is to comprehensively analyze the cytokine profile and the tumor immune infiltrate in the tumor microenvironment and to investigate its prognostic significance in patients with radically resected lung adenocarcinoma.
Study Type
OBSERVATIONAL
Enrollment
300
Overall survival
Association of tumor microenvironment with overall survival
Time frame: From date of surgery until the date of death from any cause assessed up to 100 months
Recurrence-free survival
Association of tumor microenvironment with recurrence-free survival
Time frame: From date of surgery until the date of first documented progression or date of death from any cause, whichever came first, assessed up to 100 months
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