In this study, the SCI patients were sub-grouped on the basis of symptoms into symptomatic and asymptomatic groups and measured HRV during resting and tilt up tests to compare their cardiovascular autonomic functions.
In study protocol and the subjects were asked to lie down quietly for 5 minutes, closing their eyes and avoiding talking, moving hand, legs and body, and coughing during the test. R-R interval and blood pressure were measured beat-to-beat using Finometer® PRO (Finapres Medical Systems, Amsterdam, Netherlands) for 6 minutes each in two positions, supine and 60-degree angle on the tilt table.
Study Type
OBSERVATIONAL
Enrollment
30
Pusan National University Yangsan Hospital, Geumo-ro 20, Mulgeum-eup
Yangsan, Gyeongsangnam-do, South Korea
Differences of heart rate variability between groups (OH vs non-OH, asymptomatic-OH vs symptomatic-OH group)
mean HR (heart rate), mean RR(RR interval), RMSSD (mean square of the successive R-R interval differences), SDNN (standard deviation of normal-to-normal interval), LF (low frequency) domain, HF(High frequency) domain
Time frame: at the test time (15minutes)
Logistic regression analysis of heart rate variability variables according to OH and presence of symptom
the investigators conducted logistic regression analysis to evaluate the significance and impact of HRV variables associated with orthostatic hypotension and its symptoms in spinal cord injury patients.
Time frame: at the test time (15minutes)
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