Oral iron supplements are a cornerstone therapy for treating iron deficiency and iron deficiency anemia, aiming to replenish low iron levels in the body. These supplements typically contain various iron salts, such as ferrous sulfate, ferric maltol, ferrous gluconate, and ferric pyrophosphate. Advancements in carrier systems, such as microencapsulation or complexation can enhance the absorption and bioavailability of iron supplements. By improving absorption, these carrier systems may mitigate gastrointestinal side effects and increase the efficacy of iron therapy.
This multicenter, randomized, double-blind parallel-group, clinical trial study aims to conduct a comparative analysis of the effectiveness of oral ferric maltose, vs Sucrosomial iron. The study seeks to evaluate their efficacy in treating iron deficiency or iron deficiency anemia, two prevalent conditions associated with low iron levels in the body. This research aims to provide valuable insights into potential difference in these two iron supplement formulations, both in terms of relative effectiveness and potential GI side effects. This comparative analysis may guide healthcare providers in selecting the most suitable oral iron supplement based on individual patient characteristics, ultimately optimizing treatment outcomes and improving patient care.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
59
30 mg capsule
30 mg capsule
Mayo Hospital
Lahore, Punjab Province, Pakistan
DHQ Hospital Narowal
Narowal, Punjab Province, Pakistan
Civil Hospital Kotri Distt Jamshoro
Kotri, Sindh, Pakistan
Changes in the serum iron concentration
Increase in the circulatory iron levels
Time frame: 6 weeks
Changes in the serum ferritin concentration
Increase in the circulatory ferritin levels
Time frame: 6 weeks
Change in blood Hemoglobin (Hb) levels
Increase in the blood (Hb) levels
Time frame: 6 weeks
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