Effect of Aerobic Exercise in Patients With Essential Hypertension

TC Erciyes University138 enrolled

Overview

The goal of this observational study is to evaluate the effects of a supervised aerobic exercise training program on weight loss, functional capacity, quality of life (QoL), and depression levels in patients with essential hypertension.

Patients who chose the treatment type according to personal preferences were divided into two groups: Group 1(n:91) exercised for six weeks, five sessions per week under the supervision of a medical doctor in the aerobic exercise laboratory, and group 2(n:47) was advised to maintain dietary habits and physical activity levels. Body weight, serum lipid levels, functional capacity, QoL, and depression level of all the participants were evaluated at baseline and 6 weeks later.

Study Type

OBSERVATIONAL

Enrollment

138

Conditions

Aerobic Exercise Essential Hypertension

Interventions

Supervised Aerobic ExerciseOTHER

Group 1 exercised for six weeks, five sessions per week under the supervision of a medical doctor in the aerobic exercise laboratory.

Eligibility

Sex: ALLMin age: 18 YearsMax age: 75 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Over 18 years of age, * Absence of concomitant other metabolic and cardiovascular diseases. Exclusion Criteria: * Having suffered an event of ischaemic heart disease (\<6 months), * Secondary hypertension, * Hypertrophic obstructive cardiomyopathy, * Congestive heart failure, * Uncontrolled cardiac arrhythmia, * Thyroid dysfunction, * Diabetes mellitus, * Symptomatic peripheral arterial occlusive disease, * Aortic insufficiency or stenosis, * Pulmonary or heart disease with dyspnoea at small or moderate effort, * An outbreak of orthopedic problems on hip, knee or ankles, such as arthroplasty, contracture or severe osteoarthritis, * Using of antidepressant or anxiolytic drugs, * Pregnancy, * Cognitive disfunction.

Locations (1)

Selcuk University Faculty of Medicine

Konya, Turkey (Türkiye)

Outcomes

Primary Outcomes

Body weight

kilograms

Time frame: was measured at the pre-treatment period and the post-treatment 6th week for all the participants by the same physician.

Blood samples

Serum total cholesterol, high-density lipoprotein (HDL) cholesterol, low-density lipoprotein (LDL) cholesterol, very-low-density lipoprotein (VLDL) cholesterol, and triglycerides

Time frame: Twelve-hour fasting blood samples were collected between 6.00 am, and 10.00 am at baseline and week 6.

The functional capacity

The 6MWT test and the estimated metabolic equivalents or METs were used performed to evaluate functional capacity.

Time frame: 6MWT was assessed in face-to-face interviews before and immediately after the treatment was completed.

Quality of Life

Quality of life was assessed with Short Form-36 (SF-36).

Time frame: SF36 was assessed in face-to-face interviews before and immediately after the treatment was completed.

Depression level

Depression level was assessed Beck Depression Inventory (BDI).

Time frame: BDI was assessed in face-to-face interviews before and immediately after the treatment was completed.

Data from ClinicalTrials.gov

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