Efficacy and Safety of Carrimycin Tablets in HLH Patients With Carbapenem-resistant Infections

Inclusion Criteria: * Met HLH-2004 diagnostic criteria; * Active infection； * Empirical treatment with carbapenems did not respond after 72 hours； * Age \>18 years old, no gender limitation; * Ability and willingness to adhere to the study visit schedule and all protocol requirements. Exclusion Criteria: * Other antibiotics should be selected according to the results of drug sensitivity； * Systemic antibiotics other than carbapenems are used with 72 hours； * Inability to take oral medications due to disease of gastrointestinal tract； * Severe liver insufficiency; * Expected survival time \< 1 month; * Pregnant or breasting-feeding women; * Allergic to Carrimycin tablets; * Active hepatitis B or hepatitis C infection; * Patients with HIV infection; * Patients with other contraindications considered unsuitable for participation in this study.