Various studies have shown that the milk of a preterm infant differs from that of a term infant in the composition of micronutrients, vitamins, macronutrients, carbohydrates and proteins. The study of lipidomic is of particular interest because the role of fatty acids is known both as essential constituents of cell membranes and as molecules actively involved in energy metabolism. The study of human milk would offer the advantage of offering the best type of nutrition for the newborn at each specific period of life, in the event of a lack of mother's milk.
Mother's milk is the best food for the newborn as it is the only one capable of providing species-specific nutrition, guaranteeing everything necessary for the growth and maturation of a child. Mother's milk has the property of satisfying metabolic needs by changes in the composition of nutrients, which are different at each stage of life. Various studies have shown that the milk of a preterm infant differs from that of a term infant in the composition of micronutrients, such as vitamins, macronutrients, carbohydrates and proteins. The metabolomic study of human milk would offer the advantage of offering the best type of nutrition for the newborn at each specific period of life, in the event of a lack of mother's milk. This is particularly important in a Neonatal Intensive Care Unit, where it is essential to ensure timely adequate enteral nutrition. This is possible if a bank of donated human milk is available. The study of lipidomics is of particular interest, as the role of fatty acids is known both as essential constituents of cell membranes and as molecules actively involved in energy metabolism. Therefore, the benefit deriving from an adequate dietary intake in a constantly evolving organism such as that of a newborn is extremely important.
Study Type
OBSERVATIONAL
Enrollment
66
Mothers will breastfeed their newborns
Department of Pharmacy, University of Salerno
Salerno, Naples, Italy
Department of Woman and Child, Buon Consiglio Fatebenefratelli Hospital
Napoli, Napoli, Italy
Quantification of essential long-chain polyunsaturated fatty acids in human milk
To assess the concentrations of α-Linoleic acid (µg/mL) in human milk
Time frame: 7 days after delivery
Quantification of essential long-chain polyunsaturated fatty acids in human milk
To assess the concentrations of Eicosapentaenoic acid (µg/mL) in human milk
Time frame: 7 days after delivery
Quantification of essential long-chain polyunsaturated fatty acids in human milk
To assess the concentrations of Docosahexaenoic acid (µg/mL) in human milk
Time frame: 7 days after delivery
Quantification of essential long-chain polyunsaturated fatty acids in human milk
To assess the concentrations of Arachidonic acid (µg/mL) in human milk
Time frame: 7 days after delivery
Quantification of essential long-chain polyunsaturated fatty acids in human milk
To assess the concentrations of Linoleic acid (µg/mL) in human milk
Time frame: 7 days after delivery
Quantification of essential long-chain polyunsaturated fatty acids in human milk
To assess the concentrations of α-Linoleic acid (µg/mL) in human milk
Time frame: 1 month after delivery
Quantification of essential long-chain polyunsaturated fatty acids in human milk
To assess the concentrations of Eicosapentaenoic acid (µg/mL) in human milk
Time frame: 1 month after delivery
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Quantification of essential long-chain polyunsaturated fatty acids in human milk
To assess the concentrations of Docosahexaenoic acid (µg/mL) in human milk
Time frame: 1 month after delivery
Quantification of essential long-chain polyunsaturated fatty acids in human milk
To assess the concentrations of Arachidonic acid (µg/mL) in human milk
Time frame: 1 month after delivery
Quantification of essential long-chain polyunsaturated fatty acids in human milk
To assess the concentrations of Linoleic acid (µg/mL) in human milk
Time frame: 1 month after delivery