Regrowth of amputated fingertips presents a unique regenerative healing process in mammals, with subcutaneous volume regrowth, restoration of the dactylogram, and suppression of scar formation. In addition, wound healing from split-thickness donor sites shows almost scar-free healing. Transcriptome analysis is necessary to better understand the specific healing mechanisms of these two wound entities. Since no data are available to date, this study aims to fill the gap.
Regrowth of amputated fingertips presents a unique regenerative healing process in mammals, with subcutaneous volume regrowth, restoration of the dactylogram, and suppression of scar formation. In addition, wound healing from split-thickness donor sites shows almost scar-free healing. Transcriptome analysis is necessary to better understand the specific healing mechanisms of these two wound entities. Since no data are available to date, this study aims to fill the gap.
Study Type
OBSERVATIONAL
Enrollment
75
Digit Tip Wound Exudate Sample Collected while Dressing Change
Split Skin Donor Site Wound Exudate Sample while Dressing Change
University of Schleswig-Holstein
Lübeck, Schleswig-Holstein, Germany
Differences in RNA-Expression pattern
Differences in RNA-Expression pattern between Digit Tip Wound and Split Skin Donor Site Wound
Time frame: 5 Weeks
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.