Characteristics of Trachomatous Corneal Opacity in Fayoum University Hospital

Omar Said50 enrolled

Overview

The purpose of this study is to assess the characteristics of trachomatous corneal opacity in patients with signs of trachoma using Anterior segment Optic coherence tomography and Pentacam

After approval of the local institutional ethics committee and local institutional review board, patient presented to Fayoum University Hospital was examined for corneal opacity with signs of trachoma after a detailed informed consent was signed by eligible patients and investigated by Anterior Segment Optic coherence Tomography and Pentacam. Descriptive statistics were presented in the form of mean and standard deviation for numerical variables while numbers and percentages are used for the categorical variables. Paired samples t-test was used to study anterior segment Optic Coherence tomography and pentacam in evaluating corneal thickness. Bland-Altman plot was used to study the agreement between the two methods IBM SPSS version 28 for Windows software was used for the analysis and Stata 16 was used for the Bland-Altman plot. A p-value of \< 0.05 was considered significant.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Corneal Opacity

Interventions

Corneal topographyDIAGNOSTIC_TEST

AS-OCT,PENTACAM

Eligibility

Sex: ALLHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * patients with corneal opacity accompanied by signs of trachoma Exclusion Criteria: * corneal opacity due other causes * history of corneal surgery

Locations (1)

Fayoum University

Al Fayyum, Egypt

Outcomes

Primary Outcomes

Corneal imaging

AS-OCT and PENTACAM in patients with trachomatous corneal opacity

Time frame: we will recruit patients who meer the inclusion criteria during the study period february-August 2022

Data from ClinicalTrials.gov

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