This randomized double blinded trial seeks to determine whether tranexamic acid (TXA) is an efficacious treatment for contraceptive induced menstrual changes (CIMC) including irregular, bothersome bleeding caused by the etonogestrel subdermal contraceptive implant (ENG implant). Participants will be randomized into the TXA treatment arm or a placebo. They will begin taking the medication after three consecutive days of bleeding. Participants will track their bleeding using an automated text message service
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
65
1300mg TXA taken three times per day for five days
Placebo pills taken three times daily for five days.
Oregon Health & Science University
Portland, Oregon, United States
Amenorrhea days
The difference in mean days without bleeding across 30-day reference period between the treatment and placebo groups.
Time frame: 30 days
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