Efficacy of Autologous Adipose Derived Stromal Vascular Fraction for Musculoskeletal Conditions

N/ANot Yet RecruitingNCT06000670

Dubai Health Authority300 enrolled

Overview

clinical efficacy of autologous stromal vascular fraction SVF,for inflammatory and degenerative conditions of the knees

to evaluate the clinical effectiveness of point of care autologous adipose derived stromal vascular fraction (SVF) alone or in combination with exosomes,for inflammatory and degenerative conditions of the knees.

Study Type

INTERVENTIONAL

Allocation

Purpose

OTHER

Masking

NONE

Enrollment

300

Conditions

Knee Osteoarthritis

Interventions

stromal vascular fraction injection in the osteoarthritic kneePROCEDURE

stromal vascular fraction harvested from mid abdominal wall under sedation and seperated from fat using mechanical centrifugation .injection of 5 cc of the SVF in the affected knee.

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * knee osteoarthritis any grade * knee chondromalacia grade 2 and above Exclusion Criteria: * active HIV * pregnant women * Mental disease * severe cardio vascular disease * severe coagulation disorders * infected tissues * patients on other experimental studies within 3 months

Outcomes

Primary Outcomes

change in pain level

visual analog scale 0-10 ( 10 being worst)

Time frame: 2 years

Secondary Outcomes

percentage cartilage thickness change

as measured by MRI

Time frame: 2 years

Central Contacts

Amer Mansour, MD

CONTACT

+971502983375 dramermansour@gmail.com

mazen sawaf, MD

CONTACT

+971504545266 drmax@novomed.com

Data from ClinicalTrials.gov

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