Comparison Of Outcome Of Microneedling With Autologous PRP Vs Microneedling With Topical Insulin In Treatment Of Post Acne Atrophic Scars.

Jinnah Postgraduate Medical Centre50 enrolled

Overview

Microneedling with topical INSULIN is a simple, effective tool for building body's new collagen layers and thus an alternative to all erosive techniques such as lasers, peels. The skin responds to fine punctures with the release of growth factors. 8 It is a safe procedure that can be performed in the office without complications, with a good cost-benefit because it is economically viable without any effect on patient's daily activities. 9

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

ATROPHIC ACNE SCARS

Interventions

PRP( platelet rich plasma) and Insulin humanDRUG

Microneedling with autologus PRP reduces inflammationin acne scars. Insulin human is a new topical drug which is used nowadays for acne scars as it is more effective in producing collagen formation as well as new blood vessel formation

Eligibility

Sex: ALLMin age: 20 YearsMax age: 50 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * postacne atrophic scars ≥ 2 on Goodman and Baron's acne scar-grading system * Either gender. * Age 20-50 years. Exclusion Criteria: * lactation and pregnancy * skin cancers and infection * photosensitivity like SLE ,XP * use of RETINOIDS in last 6 months.

Locations (1)

JPMC

Karachi, Sindh, Pakistan

Outcomes

Primary Outcomes

Efficacy of Topical Insulin R with microneedling versus Platelets rich plasma in atrophic acne scars

Efficacy will be assessed by using Goodman and Baron Qualitative Scar Grading System

Time frame: Efficacy will be assesed upto 4 months.

Data from ClinicalTrials.gov

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