The results of contemporary studies suggest an association between inflammatory periodontal disease and pregnancy and delivery complications. The aim of this study was to assess the association between periodontal disease, clinical periodontal parameters and pregnancy or delivery complications in type 1 diabetes mellitus and non-diabetic pregnant women.
The results of contemporary studies suggest an association between inflammatory periodontal disease and pregnancy and delivery complications. The aim of this study was to assess the association between periodontal disease, clinical periodontal parameters and pregnancy or delivery complications in type 1 diabetes mellitus and non-diabetic pregnant women. Methods: 15 type 1 diabetes mellitus and 15 non-diabetic primiparous women were enrolled in the prospective "case-control" study. Investigators compared periodontal status, levels of glycosylated haemoglobin (HbA1c), high sensitivity C-Reactive Protein (hs-CRP), gestational week of birth, birth weight of a newborn and pregnancy or delivery complications (C-section, pre-eclampsia) between the groups.
Study Type
OBSERVATIONAL
Enrollment
30
Analysis of post-delivery reports for pregnancy and/or delivery complications.
Measuring clinical periodontal parameters for assessing presence of periodontal disease.
Number of Delivery and/or Pregnancy complications
Yes/No
Time frame: Day of delivery
Number of C-section
Yes/No
Time frame: Day of delivery
Number of pregnant women with Pre-eclampsia
Yes/No
Time frame: Between 28th and 34th week of gestation
Number of Pre-term births GWOB (Gestational week of birth) ≤ 37th week
Yes/No
Time frame: Day of delivery
GWOB - Gestational week of birth
Week number
Time frame: Day of delivery
number of Births with weight ≤ 2500 g
Yes/No
Time frame: Day of delivery
Birth weight
Weight in kg
Time frame: Day of delivery
Number of pregnant women with Periodontal disease
Yes/No
Time frame: Between 28th and 34th week of gestation
Age
Age
Time frame: Between 28th and 34th week of gestation
BMI (Body mass index)
Body mass index - measure of body fat based on height and weight (BMI = Weight (kg) / Height (m)²)
Time frame: Between 28th and 34th week of gestation
PPD (Probing pocket depth)
Probing pocket depth (measured on 6 sites around teeth, unit: mm)
Time frame: Between 28th and 34th week of gestation
CAL (Clinical attachment loss)
Clinical attachment loss (measured on 6 sites around teeth, unit: mm) - This is the measurement of the position of the soft tissue attachment in relation to the cemento-enamel junction (CEJ). Two measurements are used to calculate the CAL: the probing depth and the distance from the gingival margin to the CEJ.
Time frame: Between 28th and 34th week of gestation
percantage of sites with BOP (Bleeding on probing)
Bleeding on probing, Yes/No after probing pocket depth measurement 6 sites around each tooth. Unit: %
Time frame: Between 28th and 34th week of gestation
TPIB (Total periodontal inflammatory burden)
Total periodontal inflammatory burden - measures of average teeth neck circumferences by tooth type, probing depth (PD) and bleeding on probing (BOP). The subgingival area for each tooth was calculated by multiplying 1/6th of the average cervical circumference of the tooth with each of the six measurements of probing depth. The sum of subgingival areas of all present teeth in a subject represented the total subgingival area of an individual.
Time frame: Between 28th and 34th week of gestation
TBPW area (Total bleeding periodontal wound)
Total bleeding periodontal wound - measures of average teeth neck circumferences by tooth type, probing depth (PD) and bleeding on probing (BOP). The subgingival area for each tooth was calculated by multiplying 1/6th of the average cervical circumference of the tooth with each of the six measurements of probing depth. The sum of subgingival bleeding areas of all present teeth in a subject represented the total subgingival area of an individual.
Time frame: Between 28th and 34th week of gestation
Percantage of HbA1C (Glycosylated haemoglobin)
Glycosylated haemoglobin, Unit: %
Time frame: Between 28th and 34th week of gestation
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