Consecutive obstetric patients attending routine antenatal visits were enrolled in this ongoing registry. A standardized 2D transthoracic echocardiogram (TTE) protocol was employed. Ejection fraction (EF) was quantified using biplane Simpson's method.
Consecutive obstetric patients attending routine antenatal visits were enrolled in this ongoing registry. A standardized 2D transthoracic echocardiogram (TTE) protocol was employed, including parasternal long and short, apical 4- and 2-chamber views. Continuous wave and pulse wave Doppler were used to assess left ventricular outflow tract (LVOT) gradients. Left ventricular (LV) function was quantified using biplane Simpson's method and visually assessed by two independent readers. Patients with significant valve disease or congenital heart disease underwent complete TTE. Those diagnosed with LV dysfunction or other cardiovascular diseases (CVD) were referred to the Cardio-Obstetrics clinic for further management and long-term follow-up.
Study Type
OBSERVATIONAL
Enrollment
10,000
National Institute of Cardiovascular Diseases (NICVD)
Karachi, Sindh, Pakistan
RECRUITINGNumber of participants found to have abnormal left ventricular function
Prevalence of Left ventricular dysfunction (Ejection Fraction\<55%)
Time frame: At the time of screening echocardiogram
Number of participants found to have abnormal heart valve function
Structural heart abnormalities (valvular heart lesions classified as mild, moderate and severe)
Time frame: At the time of screening echocardiogram
Number of participants found to have adverse Maternal outcomes
Maternal Mortality, Cardiogenic shock
Time frame: At the time of delivery
Number of participants found to have adverse Fetal outcomes
Infant Mortality, Infant birth weight (kg)
Time frame: At the time of delivery
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