The aim of the study is to confirm that daily supplementation with a product containing a standardized combination of polyphenol-rich extracts has a protective effect against potential blue-light-induced damage to retinal cells.
Randomized, double-blind, parallel study conducted under medical supervision on a group of 54 volunteers exposed to blue-light for 6-8h a day. Patients receive one of the investigational products or placebo for 6 weeks. Study parameters: OCT (optical coherence tomography), Amsler test, Computerized Perimetry, Schirmer test. In addition, subjective symptoms will be assessed using the Visual Analog Scale (VAS) method and a Dry Eye-Related Quality-of-Life Questionnaire. The studied parameters will be measured before and after supplementation.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
DOUBLE
Enrollment
22
Extracts from the fruits of Vaccinium myrtillus L. + Aronia Melanocarpa (Michx.) Elliot + Lonicera caerulea var. Kamtschatica, rutin, vitamin B6, vitamin B12, folic acid Single oral dose - 2 capsules
Extracts from the fruits of Vaccinium myrtillus L. + Aronia Melanocarpa (Michx.) Elliot + Lonicera caerulea var. Kamtschatica Single oral dose - 2 capsules
Single oral dose - 2 capsules
Centrum Zdrowia Eter-Med sp. z o.o.
Gdansk, Poland
DEQS (Dry Eye-Related Quality-of-Life) index
Subjective symptom questionnaire assessment
Time frame: Baseline, 6 weeks
Visual Analogue Scale
Subjective symptom assessment
Time frame: Baseline, 6 weeks
Optical Coherence Tomography
An OCT provides cross sectional images of the retina to enable early detection and treatment of ocular disease
Time frame: Baseline, 6 weeks
Amsler test
Amsler grid usually help detecting defects in central 20 degrees of the visual field
Time frame: Baseline, 6 weeks
Schirmer test,
Schirmer test quantitatively measures the tear production by the lacrimal gland
Time frame: Baseline, 6 weeks
Computerized Perimetry
Computerized Perimetry is used to evaluate visual function
Time frame: Baseline, 6 weeks
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