Adhesive capsulitis, is a common problem characterized by the insidious onset of glenohumeral pain and limitation of shoulder motion in all planes. Clinically, frozen shoulder could be divided into freezing, frozen and thawing stage. The treatments of frozen shoulder are mainly conservative, including non-steroidal anti-inflammatory medications and physiotherapy. Due to debilitating pain at a certain stage and protracted clinical course, intra-articular corticosteroid injection in the early stages of idiopathic adhesive capsulitis has long been used to treat adhesive capsulitis with satisfactory result. However, intra-articular steroid injection still raise some controversy and is still considered too invasive for some patients. Low-level laser therapy (LLLT) is a safe and non-invasive alternative. LLLT can employ photo-biomodulation effects to help normalize cellular functions and is considered to have partial effect in many shoulder soft tissue disorders. Possible mechanisms include increasing adenosine triphosphate production, fibroblast activity and collagen synthesis. One prospective cohort study has shown that LLLT can be effective in the management of the early phase (less than 6 weeks of disease onset) of adhesive capsulitis of the shoulder in elderly who failed to respond to conventional physical therapy and nonsteroidal anti-inflammatory medications and improvement was found maintained up to 2 years. To this date, no randomized controlled study has been made to establish the possible role of LLLT as an adjuvant therapy on adhesive capsulitis. Also, no study has researched the effect of LLLT on patient with later stage/chronic phase of adhesive capsulitis. The objective of this paper is to report the clinical result of a study on the efficacy of LLLT as an add-on therapy in the management of adhesive capsulitis.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
50
Low-level laser therapy (LLLT), three time each week, 10 minutes each time, during the first 8 weeks of the treatment trial.
Conventional physical therapy will be applied three time each week, for 12 weeks
National Taiwan University Hospital
Taipei, Taiwan
RECRUITINGShoulder range of motion
Shoulder flexion, abduction, external rotation, internal rotation
Time frame: 24 weeks after enrollment
Shoulder pain score
Visual analogue scale for pain during shoulder motion (scale from 0 to 10, with higher scores mean worse outcome)
Time frame: 24 weeks after enrollment
Functional evaluation
Shoulder Pain Disability Index (SPADI)
Time frame: Immediate upon enrollment, and 8, 12, 24 weeks after enrollment
Ultrasound examination
Thickness of coracohumeral ligament and inferior glenohumeral capsule
Time frame: Immediate upon enrollment, and 8, 12, 24 weeks after enrollment
Functional evaluation
Disability of the Arm, Shoulder, and Hand (DASH) questionnaire
Time frame: Immediate upon enrollment, and 8, 12, 24 weeks after enrollment
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