Patients undergoing gastrointestinal tumor surgery are prone to delayed recovery and postoperative cognitive dysfunction due to greater trauma and longer operation time. Pre-analgesia can reverse the effects of nociceptive stimulation on recovery from general anesthesia and postoperative cognitive function. Intravenous injection of non-steroidal drugs can effectively reduce postoperative pain and the use of opioids. Therefore, This study selected acetaminophen mannitol injection for preemptive analgesia to observe the effects on anesthesia recovery time and postoperative cognitive function of patients undergoing gastrointestinal tumor surgery, providing new ideas for reducing cognitive dysfunction in patients undergoing gastrointestinal tumor surgery
By administering acetaminophen to patients with gastrointestinal tumors before surgery, recording the time to recovery from anesthesia, and assessing cognitive function status by CAM on the first, third, and seventh day after surgery
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
SINGLE
Enrollment
100
Intravenous acetaminophen was administered 30 minutes before anesthesia
Intravenous acetaminophen was administered 30 minutes before anesthesia
Affiliated Hospital of nantong University
Nantong, Jiangsu, China
RECRUITINGPostoperative delirium
The confusion assessment method (CAM) was used to assess postoperative cognitive dysfunction
Time frame: 1/3/7 days after the surgery
Recovery time
The postoperative recovery time was recorded
Time frame: immediately after the surgery
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