Acute heart failure (AHF) is defined as new or worsening of symptoms and signs of heart failure and is the most frequent cause of unplanned hospital admission in elderly patients. N-terminal pro-brain natriuretic peptide (NT-pro-BNP) is one of the most developed prognostic markers for AHR patients and. NT-pro-BNP has limitations in terms of diagnostic or predictive accuracy in patients with chronic kidney disease (CKD). Plasma proteomics have the potential to examine underlying pathophysiological and prognostic roles, so we compared the plasma proteomic signature to predict outcomes of patients with or without CKD hospitalized for AHF.
Study Type
OBSERVATIONAL
Enrollment
155
Cheng Hsin General Hospital
Taipei, Baitou District, Taiwan
RECRUITINGmajor adverse cardiovascular events
mortality, acute myocardial infarction, acute stroke, and heart failure hospitalization
Time frame: 1 year
major adverse kidney events
mortality, new end-stage renal disease, and 30% decline in estimated GFR
Time frame: 1 year
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