Acupuncture Combined With Nimodipine for Prevention of Post-stroke Dementia

Yuzhen Pan40 enrolled

Overview

To observe the clinical efficacy of TCM acupuncture combined with western medicine nimodipine for prevention of post-stroke dementia by comparing with clinical conventional treatment methods.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

SINGLE

Enrollment

Conditions

Post-stroke Dementia

Interventions

The control group received oral nimodipine tabletsDRUG

The control group received oral nimodipine tablets

Eligibility

Sex: ALLMin age: 40 YearsMax age: 85 Years

Medical Language ↔ Plain English

Inclusion Criteria: 1. Definite ischemic stroke or hemorrhagic stroke confirmed by head CT / MRI examination 2. Memory or cognitive and executive dysfunction. Cognitive dysfunction will be determined after the mini mental state evaluation (MMSE) score 3. Age limited to 40-85 years, irrespective of gender 4. Stable condition, clear consciousness, no aphasia, oral medication available 5. No major comorbidity, no major depression 6. Consent and signed patient informed consent Exclusion Criteria: 1. Had serious medical conditions, such as heart, liver, kidney, or endocrine disease 2. Aphasia or hearing impairment 3. Participants in other clinical trials 4. Patients currently on medication to improve cognitive function

Locations (1)

The Second Affiliated Hospital of Anhui University of Chinese Medicine

Hefei, Anhui, China

Outcomes

Primary Outcomes

Response Rate

Time frame: 24 weeks

Secondary Outcomes

Hasegawa Dementia Scale

Time frame: 24 weeks

Montreal Cognitive Assessment

Time frame: 24 weeks

Data from ClinicalTrials.gov

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