Light and Sleep Fragmentation

Phase 4Not Yet RecruitingNCT06009289

Stanford University120 enrolled

Overview

This trial will examine scheduled exposure to bright light in the morning and afternoon as a countermeasure to sleep fragmentation in older individuals with mild cognitive impairment.

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

120

Conditions

Sleep Mild Cognitive Impairment Mood Disorders

Interventions

Light therapyBEHAVIORAL

One hour of exposure to bright light, either by being outdoors or with a phototherapy lamp if indoor

Eligibility

Sex: ALLMin age: 65 YearsMax age: 99 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Mild Cognitive Impairment * Age \>65 Exclusion Criteria: * Severe depression * Unstable psychiatric or medical disease * Acute infection

Locations (1)

Stanford University

Redwood City, California, United States

Outcomes

Primary Outcomes

Sleep fragmentation

24 hour sleep wake patterns will be quantitated with a non-parametric measure, intradaily variation

Time frame: 4 weeks

Secondary Outcomes

Cognition

Performance on the WAIS-4

Time frame: 6 months

Mood

Geriatric Depression Scale, range: 0-15 with higher scores being associated with greater depressive symptomatology

Time frame: 6 months

Central Contacts

Renske Lok, PhD

CONTACT

rlok@stanford.edu

Data from ClinicalTrials.gov

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