Management of Symptomatic Uterine Fibroids in Pregnancy by Laparotomic Myomectomy: a Prospective Cohort Study

University of Palermo28 enrolled

Overview

The frequency of women presenting with a combination of uterine fibroids and pregnancy is in-creasing nowadays. Uterine fibroids in pregnancy are an unfavorable condition in themselves and being reactive to hormonal stimuli, tending to grow, can generate symptoms of different lev-els of severity. Obstetrics and gynecologists are increasingly faced with the problem of clarifying the management tactics of pregnant patients with symptomatic fibroids, who may see their preg-nancy put at risk by these masses.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Uterine Fibroid Pregnancy Related

Interventions

Laparotomic myomectomy during pregnancyPROCEDURE

Surgical removal of symptomatic uterine fibroids in pregnancy by laparotomic access

Eligibility

Medical Language ↔ Plain English

Inclusion Criteria: * The large and giant size of UFs, which prevent the proper continuation of pregnancy and/or occupy the entire small and large pelvis, as well as invade and/or occupy the abdominal cavity. * Circulatory disorders, evidenced by necrosis of the UFs. * Atypical localization of UFs (cervical, isthmic, intraligamentary, etc.), which caused pelvic organ dysfunction (dysuric phenomena, tenesmus, impediment to the act of defecation, pelvic pain). Exclusion Criteria: * Refusal of LPTM by the patient. * Absence of urgent indication for LPTM during pregnancy.

Outcomes

Primary Outcomes

continuation of pregnancy

Pregnancy continuation after surgery.

Time frame: 5 months

Secondary Outcomes

Fetal outcome

Assessed by APGAR 1 and 5 min, birth weight, and fetal conformation.