Phase 1 Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of KN510, KN713

Inclusion Criteria: 1. Male and female adults aged 19-75 years 2. Unresectable advanced or metastatic solid tumors that are confirmed as progressive disease (PD) after the standard of care currently known to have clinical benefits, or for which no currently available standard therapies exist due to intolerance, ineligibility, rejection, etc. 3. At least one measurable lesion per RECIST ver1.1 4. The Eastern Cooperative Oncology Group (ECOG) performance status (PS) of 0-1 5. Life expectancy of at least 12 weeks 6. Confirmed adequate hematologic, renal, and hepatic functions according to the following criteria (Laboratory tests may be repeated once during the screening period): A. Hematological function * Absolute neutrophil count (ANC) ≥1,500/μL * Hemoglobin ≥9 g/dL * Platelet count ≥100,000/μL B. Renal function: Creatinine clearance (CrCl\*) \>60 mL/min \*Cockcroft-Gault equation C. Hepatic function * Aspartate aminotransferase (AST) ≤3.0 × ULN * Alanine aminotransferase (ALT) ≤3.0 × ULN (AST/ALT ≤5 × ULN, if hepatic metastasis is confirmed) * Total bilirubin ≤1.5 × ULN (with the exception of confirmed Gilbert's syndrome) D. Coagulation function: Prothrombin time international normalized ratio (PT INR) and activated partial thromboplastin time (aPTT) ≤1.5 × ULN 7. Voluntary written consent to participate in this study Exclusion Criteria: 1. Hypersensitivity to the active ingredient or excipients of KN510 or KN713 2. Any of the following medical (surgical) history or comorbidities at the screening visit: A. Major surgery that requires general anesthesia or a respiratory assist device within 4 weeks prior to screening (within 2 weeks for video-assisted thoracoscopic surgery \[VATS\] or open-and-closed \[ONC\] surgery) B. Clinically significant arrhythmia, acute myocardial infarction, unstable angina, or NYHA Grade Ⅲ or Ⅳ heart failure within 24 weeks prior to screening C. Pulmonary thrombosis, deep vein thrombosis, or bronchial asthma, obstructive pulmonary disease or other life-threatening severe lung disorder (e.g., acute respiratory distress syndrome, lung failure) considered ineligible for participation in the study within 24 weeks prior to screening D. Grade 3 or higher active infectious conditions which require systemic antibiotics, antivirals, etc. within 2 weeks prior to screening E. Clinically significantly symptomatic or uncontrolled central nervous system or brain metastases at screening (except for patients who have discontinued systemic corticosteroid treatment at least 4 weeks prior to baseline and have been stable for at least 4 weeks) F. Hematologic malignancy including lymphoma at screening G. Uncontrolled hypertension (systolic blood pressure \[SBP\]/diastolic blood pressure \[DBP\] ≥160/100 mmHg) at screening H. Parkinson's disease, parkinsonian symptoms, tremors, restless leg syndrome, and other related movement disorders at screening I. Active hepatitis B\* or C† at screening \* Defined as HBsAg positive at screening; patients on stable antiviral regimen may participate † Defined as HCV Ab positive at screening; patients who test negative for HCV RNA may participate J. Known human immunodeficiency virus (HIV) infection K. Difficulty (e.g., problem swallowing) in oral administration of KN510 and KN713 or disease (celiac disease, Crohn's disease, or intestinal resection which is clinically significant or impacts absorption) which impacts absorption at screening L. History or suspected symptoms of gastroesophageal reflux disease (GERD) such as gastric ulcer, duodenal ulcer, and reflux esophagitis at screening M. History of autoimmune diseases at screening N. Deemed ineligible for the study for having a comorbidity that is uncontrolled or requires treatment 3. Prior treatment with any of the following medications within 2 weeks prior to screening A. Proton pump inhibitors (PPIs) other than the IP B. Strong CYP2C19 inducers: Rifampicin, Apalutamide, Rifamycin, Rifaximin, Rifapentine C. Strong CYP2C19 inhibitors: Fluvoxamine, Ticlopidine, Chloramphenicol, Delavirdine, Gemfibrozil, Stiripentol, Fluoxetine, Imipramine, Clomipramine, Lansoprazole, Isoniazid, Zafirlukast, Tioconazole, Miconazole D. CYP2C19 substrates: Clopidogrel, Citalopram, Cilostazol, Phenytoin, Diazepam E. Vitamin K antagonists: Warfarin, Dicoumarol, Phenindione, Phenprocoumon, Acenocoumarol, Ethyl biscoumacetate, Fluindione, Clorindione, Diphenadione, Tioclomarol F. Antiretrovirals: Rilpivirine-containing products, Atazanavir, Nelfinavir, Saquinavir G. High dose Methotrexate (≥1000 mg/m2) H. Digoxin I. Cefditoren, Cefuroxime J. Levoketoconazole K. St John's Wort L. Bromopride, Metoclopramide M. Other anti-cancer therapies (chemotherapy, radiotherapy, immunotherapy, targeted therapy, hormone therapy, etc. other than the IP) which could impact the efficacy results during the study (However, local radiotherapy to alleviate ostalgia, bronchial obstruction, skin lesion, etc. are permitted. The total irradiation dose must be within the site-specific reference range for palliative therapy, and irradiation sites must be excluded from the tumor assessment.) N. Requiring continued treatment with systemic corticosteroids at a dose of prednisone \>10 mg/day or equivalent (with exceptions of topical use such as intra-articular, intranasal, intraocular, and inhalational administration and temporary use for treatment and prevention of allergic reactions to a contrast agent or AEs \[e.g., vomiting\]) 4. Pregnant or lactating women, or women of childbearing potential and men who are unwilling to remain abstinent or use adequate methods of contraception\* during the study and for 3 months after IP administration \* Adequate methods of contraception: * Hormonal contraceptives * Placement of an intrauterine device or intrauterine system * Surgical sterilization (vasectomy, tubal ligation, etc.) 5. Received/Used another investigational agent/device within 4 weeks (or 5 half-lives) prior to screening 6. Ineligibility or inability to participate in the study in the judgment of the investigator