The objective of this study was to evaluate the safety and efficacy of early submaximal balloon angioplasty combined with medical therapy vs medical therapy alone for minor stroke/transient ischemic attack with intracranial atherosclerosis etiology.
In this study, 416 patients with minor strokes or transient ischemic attacks due to symptomatic intracranial atherosclerotic stenosis within one week of the onset of last ischemic symptoms from 20 centers in China were enrolled. The observation group received early submaximal balloon angioplasty, while the control group received only medical therapy. Two groups will be followed up for 1 year to evaluate the safety and efficacy of early submaximal balloon angioplasty combined with medical therapy vs medical therapy alone for minor stroke / transient ischemic attack with intracranial atherosclerosis etiology.
Study Type
OBSERVATIONAL
Enrollment
416
The goal of submaximal balloon angioplasty is to use the balloon to improve the stenosis of the criminal artery by more than 20%.
The First Hospital of Jilin University
Changchun, Jilin, China
RECRUITINGStroke or death within 30 days or ischemic stroke in the culprit artery territory from 30 days to 1 year
Stroke or death within 30 days or ischemic stroke in the culprit artery territory from 30 days to 1 year
Time frame: 30 days, 1 year
Stroke or death within 30 days after enrollment
Stroke or death within 30 days after enrollment
Time frame: 30 days
Ischemic stroke in the territory of criminal artery from 30 days to 1 year after enrollment
Ischemic stroke in the territory of criminal artery from 30 days to 1 year after enrollment
Time frame: 1 year
Restenosis rate of criminal artery within 1 year after enrollment
Restenosis rate of criminal artery within 1 year after enrollment
Time frame: 1 year
Evaluation of neurological function improvement within 90 days of enrollment
Evaluation of neurological function improvement within 90 days of enrollment
Time frame: 90 days
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