The purpose of this study is to assess the clinical and immunological effect of spirulina in treatment of stage II periodontitis.
In this study, the investigators tested the effect of spirulina gel as adjunctive of scaling and root planing in treatment of stage II, grade B periodontitis in term of probing pocket depth reduction, mean gain in clinical attachment level, and level of interleukin 6.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
40
Patient were received spirulina gel in diseased sites. The process will be repeated at 7, 14, 21 days.
Patients received oral hygiene instructions and SRP of all teeth.
Kafrelsheikh University
Tanta, Egypt
Clinical attachment level
Clinical attachment level was measured at baseline, 1 and 3 months after gel application.
Time frame: 3 months
Probing pocket depth
Probing pocket depth was measured at baseline, 1 and 3 months after gel application.
Time frame: 3 months
Interleukin 6.
Enzyme linked immune-assay for the quantitative measurement of interleukin 6 concentration in gingival cervicular fluid at baseline, 1 and 3 months after gel application.
Time frame: 3 months
Plaque Index
Plaque index was measured at baseline and at 1, and 3-months post treatment.
Time frame: 3 months
Gingival index
Gingival index was measured at baseline and at 1, and 3-months post treatment.
Time frame: 3 months
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