Acute Effect of Motor-Cognitive Training

Ke'La H Porter21 enrolled

Overview

Participants will complete a functional MRI to evaluate brain activation, functional connectivity, and behavioral performance immediately before and after a training program (approximately 30 minutes). The training program will comprise of integrate neuromuscular (agility, dynamic postural stability, shuffling, rapid acceleration/deceleration, plyometrics, lateral shuffle, and core stability) and cognitive (reaction time, processing speed, task switching, decision-making, and working memory) challenges.

Study Type

INTERVENTIONAL

Allocation

Purpose

PREVENTION

Masking

NONE

Enrollment

Conditions

Injury;Sports

Interventions

Motor-Cognitive Training ProgramOTHER

The training will incorporate cognitive tasks which focus on reaction time, processing speed, working memory, cognitive flexibility, and inhibitory control using visual stimuli on a screen or through sensors which illuminate using LED lights. These cognitive tasks will be performed while also executing physical performance tasks that challenge static and dynamic postural stability, lateral movement, agility, and other movement patterns. The training session will last approximately 30 minutes and participants will complete up to 5 exercises

Eligibility

Sex: FEMALEMin age: 18 YearsMax age: 25 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Physically active Exclusion Criteria: * Injury to the muscle or bone (upper extremity, lower extremity, or back) within the past 3 months * Had musculoskeletal surgery or fracture (required open reduction internal fixation or within the last 12 months) * Had a concussion or mild head injury within the last year * Have been diagnosed with any kind of neurological, vestibular, or visual disturbance that impairs mobility * Currently taking medications that affect the central nervous system * Pregnant or suspicions of being pregnant * Have metal fragments, pins, plates, or clips, shrapnel, body piercings that cannot be removed, have surgical implants or orthodontics that cannot be removed * Have claustrophobia * Have a history of cognitive impairment

Locations (1)

University of Kentucky

Lexington, Kentucky, United States

Outcomes

Primary Outcomes

Change in brain activation

During the task-based functional MRI scan the participant will complete a task-switching cognitive task, where participants have to identify two possible shapes (circle or square), in one of two possible colors (red or blue). They will respond using a trigger under their left and right foot. The level of brain activation during the task will be captured and reported.

Time frame: 2 hours, pre-training session and immediately post-training session

Change in functional connectivity

The participant will complete a resting-state functional MRI scan in which they will lay still in the scanner. No task is performed during this scan. Functional connectivity (functionally related regions of the brain that are co-activated) during the scan will be captured and reported.

Time frame: 2 hours, pre-training session and immediately post-training session

Change in reaction time

During the task-based functional MRI scan the participant will complete a task-switching cognitive task, where participants have to identify two possible shapes (circle or square), in one of two possible colors (red or blue). They will respond using a trigger under their left and right foot. The reaction time in milliseconds will be captured. The change in reaction time from pre to post training session will be reported.

Time frame: 2 hours, pre-training session and immediately post-training session

Change in accuracy

During the task-based functional MRI scan the participant will complete a task-switching cognitive task, where participants have to identify two possible shapes (circle or square), in one of two possible colors (red or blue). They will respond using a trigger under their left and right foot. The percent of correct responses (accuracy) will be captured. The change in accuracy from pre to post training session will be reported.

Time frame: 2 hours, pre-training session and immediately post-training session

Secondary Outcomes

Data from ClinicalTrials.gov

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Demographic/Injury History Form

The demographic and injury history form is designed to capture: 1) information about the participant including age, height, weight, race, ethnicity, 2) information related to sports participation, and 3) information related to past injuries or medical conditions which are relevant to the study.

Time frame: Once, pre-training

Defense Veterans Pain Rating Scale

The Defense Veterans Pain Rating Scale is a valid 5-item scale to assess pain magnitude and pain interference. This scale ranges from 0 to 10, 0 indicating no pain/interference and 10 indicating as bas as it could be/complete interference.

Time frame: Once, pre-training

Modified Disablement In Physically Active Scale

16-item patient-reported outcome instrument that assesses physical and psychosocial status.This scale ranges from 0 to 4, 0 indicating no problem and 4 indicating severe.

Time frame: Once, pre-training

NASA Physical Activity Survey

This survey asks individuals to self-report their general physical activity over the past week. This survey ranges from 0 to 10, 0 indicating sedentary and 10 indicating high physical activity.

Time frame: Once, pre-training

Heart rate

Heart rate will be monitored with a noninvasive heart rate monitor that will be worn by the participant around the chest at the level of the xiphoid process. Resting heart rate will be collected prior to the start intervention then monitored and recorded throughout the training session.

Time frame: 35 minutes, during the training session

Average reaction time during the intervention

Average reaction time in milliseconds will be captured during the exercises via light sensors.