The goal of this retrospective observational study is to compare brain fluorodeoxyglucose-positron emission tomography (FDG-PET) of patients with autoimmune encephalitis, normal controls and patients with Alzheimer's disease (AD). The main question it aims to answer is: •is there a specific pattern of brain metabolism in patients with autoimmune encephalitis Participants data and images will be retrospectively collected from hospital records, and FDG-PET images will be analyzed by means of statistical parametric mapping (SPM). Controls will be selected from validated public databases.
Study Type
OBSERVATIONAL
Enrollment
90
Brain FDG-PET
Azienda Sanitaria Universitaria Friuli Centrale
Udine, Friuli Venezia Giulia, Italy
NOT_YET_RECRUITINGIRCCS Ospedale Policlinico San Martino
Genoa, Liguria, Italy
NOT_YET_RECRUITINGFondazione IRCCS Mondino
Pavia, Lombardy, Italy
SPM analysis of brain metabolic pattern
Pattern of brain metabolism in patients with autoimmune encephalitis compared with healthy controls and patients with Alzheimer's disease, drawn from validated published databases
Time frame: up to 6 months
Sensitivity of basal ganglia hypermetabolism
Sensitivity of basal ganglia hypermetabolism for the diagnosis of autoimmune encephalitis
Time frame: up to 6 months
Diagnostic delay
Comparison of diagnostic delay with and without FDG-PET
Time frame: up to 6 months
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Fondazione IRCCS San Gerardo dei Tintori
Monza, Monza E Della Brianza, Italy
RECRUITINGFondazione IRCCS Istituto Neurologico "Carlo Besta"
Milan, Italy
NOT_YET_RECRUITINGOspedale San Paolo
Milan, Italy
NOT_YET_RECRUITING