Antibiotics, Microbiology and Immunology in Children With Chronic Wet Cough - the AMIC Study

Inclusion Criteria: 1. Age ≥ 9 and \< 36 months. 2. Body weight ≥ 7 kg and \< 24 kg. 3. Born term with Gestational age ≥ 37 weeks. 4. Chronic wet cough for \> 4 weeks at screening and in addition average cough score last 7 days at randomization ≥ 4 points and without signs of another cause. Registration ≥ 5 days is mandatory. 5. Written informed consent obtained from both parents at inclusion. 6. The study subject must be assessed as eligible for treatment with Augmentin. Exclusion Criteria: 1. Gestational age \< 37 weeks. 2. History of acute upper or lower airway infection the last 2 weeks. 3. History of other viral or bacterial infections the last 2 weeks. 4. Episode with temperature above 38 °C during the last 2 weeks. 5. Previous diagnosed with chronic lung disease such as cystic fibrosis, primary ciliary dyskinesia, interstitial lung disease, asthma, immunodeficiency, esophagus atresia. 6. Cardiac disease, except persisting foramen ovale or ductus arteriosus. 7. Severe feeding problems/aspiration. 8. Gastroesophageal reflux suspicion or confirmed by ph measurement. 9. Suspicion of hypertrophic tonsils or adenoids 10. Episodes of bronchopulmonary obstruction suggesting asthma 11. Presence of gross neurodevelopmental delay, or suspicion of neurological disease. 12. History of known or suspected allergic reactions to amoxicillin-clavulanate or any other betalactam. 13. Episodes with haemoptysis and with unknown cause. 14. Radiographic changes other than perihilar changes confirmed by x-ray at screening. 15. At examination: Digital clubbing, hypoxia, chest wall deformity, dyspnoea at rest. 16. Parents unable to speak and/or understand Norwegian language. 17. Received systemic antibiotics within the last 6 months before inclusion. 18. Participation in another clinical intervention trial.