Validation of CARPET prognostic model for septic shock after allo-HSCT: a multicenter, prospective, and cohort study
A clinical prognostic model named CARPET model for septic shock after allo-HSCT has been developed and internally retrospectively validated. A multicenter, prospective cohort study is planned to validate this clinical prediction model again. The equation of the prediction model for 28-day mortality was as follows: Probability(28-day mortality)=(exp(Y))/(1+exp(Y)) where Y=2.343+1.328\* Time of septic shock- 0.085\* Albumin + 0.016 \* Bilirubin-0.003\*PaO2/FiO2 +0.127\*Lactate- 0.011 \* Glomerular filtration rate
Study Type
OBSERVATIONAL
Enrollment
200
For patients diagnosed with septic shock, we obtained the information in CARPET prognostic model including time of septic shock, albumin, bilirubin, PaO2/FiO2, lactate, and GFR. We calculated the CARPET risk score and the 28-day mortality probability according to CARPET logistic regression model.
Peking University Insititute of Hematology, Peking University People's Hospital
Beijing, Beijing Municipality, China
28-day mortality
Dead or alive at day 28 after septic shock diagnosis
Time frame: 28 days
ICU length of stay
Days in the ICU after septic shock diagnosis
Time frame: up to 1 year
90-day mortality
Dead or alive at day 90 after septic shock diagnosis
Time frame: 90 days
Time on ventilator
Days in need of mechanical ventilation
Time frame: up to 1 year
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