A Prospective, Single-center, Single-blind, Randomized split-face, controlled trial will be conducted. The goal of this clinical trial is to evaluate the efficacy and satisfaction of the Skinceuticals skin care product (CE) for skin repair following fraxel laser treatment and explore the medical value of fraxel laser therapy combined with Skinceuticals skin care product
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
50
Skinceuticals skin care product(CE FERULIC)+routine sun protection
Fraxel DUAL 1550/1927 Laser System
0.9% normal saline+routine sun protection
Change in erythema score
Scoring criteria: 0 (no erythema), 1 (mild erythema), 2 (moderate erythema), and 3 (severe erythema)
Time frame: at day 7 post-procedure
Change from baseline in erythema score
Scoring criteria: 0 (no erythema), 1 (mild erythema), 2 (moderate erythema), and 3 (severe erythema)
Time frame: days 1, 3 post-procedure
Change from baseline in edema score
Score 0 - no edema, score 1 - mild edema, score 2 - moderate edema, score 3 - severe edema
Time frame: days 1, 3,7 post-procedure
Change from baseline in Erythema Index (EI)
EI values were measured on both sides of their faces with a multifunctional skin tester MPA20 (Courage Khazaka, Germany) + Mexameter MX18 probe
Time frame: days 1, 3,7 post-procedure
Change from baseline in melanin index(MI)
MI values were measured on both sides of their faces with a multifunctional skin tester MPA20 (Courage Khazaka, Germany) + Mexameter MX18 probe
Time frame: days 1, 3,7 post-procedure
Change from baseline in stratum corneum water content
Time frame: days 1, 3,7 post-procedure
Change from baseline in transepidermal water loss
Time frame: days 1, 3,7 post-procedure
Change from baseline in sebum rate
Time frame: days 1, 3,7 post-procedure
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Subjects overall satisfaction
Satisfaction ratings were classified as: very satisfied, satisfied, dissatisfied, very dissatisfied
Time frame: days 1, 3,7 post-procedure
Scab and desquamation
Record the start scab formation time, start scab removal time and complete scab removal time of subjects
Time frame: days 1, 3,7 post-procedure