Hypoxia is a known factor for resistance to radiotherapy in tumors. Response to transarterial radioembolization is known to be variable between different patients even if the same dose of radiation was delivered. In this study the investigators aim to quantify the hypoxia in the primary and secondary tumors of liver with 18F-FMISO PET before radioembolization and to prove any effect of the hypoxia, if present, on the dose that should be delivered to tumor to ensure treatment response.
Study Type
OBSERVATIONAL
Enrollment
64
Imaging of hypoxia before radioembolization with 18F-Fluoromisonidazole PET.
Ankara University
Ankara, Turkey (Türkiye)
Demonstrate the effect of the hypoxia in the success of the radioembolization treatment
Demonstrate the effect of the hypoxia in the success of the radioembolization treatment
Time frame: 08/2024
The effect of the hypoxia on the dose-response relationships and required doses to achieve treatment response in the hypoxic and non-hypoxic group.
The effect of the hypoxia on the dose-response relationships and required doses to achieve treatment response in the hypoxic and non-hypoxic group.
Time frame: 08/2024
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