PRP Injections for Genitourinary Syndrome of Menopause

Inclusion Criteria: * Women (assigned female at birth) at least 18 years old with a clinical diagnosis of GSM * Sexually active with at least one episode of sexual activity per week in the preceding 4 weeks defined as follows: Partnered or solo penetrative or non-penetrative stimulation of the clitoris or vagina * English-speaking * Willingness and able to comply with the study requirements Exclusion Criteria: * Symptomatic pelvic organ prolapse protruding beyond the hymen) * History of prior vaginal mesh or midurethral mesh sling surgery * History of pelvic radiation or genital tract malignancy * Current symptomatic pelvic organ prolapse (stage II or greater) * Active vulvar dermatoses or genitourinary infection * Unable to hold anticoagulation * Hormonal replacement therapy (systemic, local, or vaginal) within 3 months of participation * Pregnancy or pre-menopausal status