The purpose of the current open-lable study was to use low-frequency repetitive transcranial magnetic stimulation (rTMS) to improve the attention deficits in a sample of adult patients suffering from attention deficit disorder. Participants received 10 sessions of rTMS over Fz (located using the EEG 10-20 international system) and underwent assessments of their attentional capacity using the gradCPT task in an fMRI scanner, before and after the intervention. Other behavioral assessments of their attention symptoms have also been conducted.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
10
Magnetic pulses delivered to the Fz area of the brain in a low frequency (1 Hz) manner.
National Brain Mapping Lab
Tehran, Iran
Change in performance
Shortened version (4 min) of the continuous go/no-go task: gradual-onset continuous performance task (gradCPT)
Time frame: Up to 10 days, i.e., before and after the completion of the 10 sessions of rTMS
Change in self-report attention scores
The 6-item ASRS-V1.1 Adult ADHD Self-Report
Time frame: Baseline, after 5 days of stimulation, after 10 days of stimulation; Range= 0-6; Higher scores represent worse outcome
Change in investigator-rated attention scores
Investigator-Rated Attention-Deficit Hyperactivity Disorder (ADHD) Rating Scale-IV (I-ADHD RS-IV) with adult prompts
Time frame: Baseline, after 5 days of stimulation, after 10 days of stimulation; Range:0 - 54; Higher scores represent worse outcome
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