This research concerns the study of language disorders of patients present in the spectrum of psychosis. It is indeed accepted that psychotic disorders are associated with language difficulties, which are only poorly highlighted thanks to reusable tools in clinical practice. These language disorders impact communication, and concern many linguistic domains, thus covering phonology, lexicon, semantics, morphosyntax and pragmatics. It therefore seems relevant to characterize these language disorders and to assess to what extent they interact with the other symptoms of the pathology, in particular the course of the thought disorder and the neuropsychological symptoms. In addition, this study is particularly interested in the interactions between working memory capacities and those related to syntax. It is intended for different patients suffering from psychotic disorders of different intensities, treated in the Psychotherapeutic Center of Nancy. Patients suffering from at-risk mental state (ARMS), first episode of psychosis (FEP) or schizophrenia will benefit from a complete language assessment, evaluating each domain mentioned above, on the expressive and understanding sides. The results of the language assessment will be compared with those of a control group in the same tests. They will also be analyzed with regard to the neuropsychological and psychiatric elements noted in the patient's medical file, in order to highlight possible associations between language skills, neuropsychological and psychiatric symptoms in this patient population.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
DIAGNOSTIC
Masking
NONE
Enrollment
90
The proposed speech and language therapy assessment will consist of a battery of standardized tests that speech and language therapists can use to assess the language skills in reception and expression of adult patients. Concerning the assessment of the interactions between working memory and semantic abilities, a complete protocol has been developed.
This scale is frequently used in psychiatry and is used to measure formal thought disorders in patients suffering from psychosis. As part of this study, it will be intended for patients suffering from schizophrenia
This scale corresponds to a rapid assessment of the psychiatric and psychological state of patients. It helps detect any psychiatric disorders. Here, it will be offered to volunteers who are part of the control group.
The purpose of this questionnaire is to approximate participants' cannabis consumption and to assess any disorders associated with cannabis consumption. It will be offered to all participants, patients and healthy controls
Centre Psychothérapeutique de Nancy
Laxou, France, France
RECRUITINGlanguage assessment performance score
complete speech therapy assessment evaluating each language domain. and is based on the completion of a speech therapy assessment test and on the assessment of language abilities by the experimental speech therapist.
Time frame: day 1
CAARMS Speech Disorganization Severity Score
CAARMS: Comprehensive Assessment of At Risk Mental State
Time frame: day 1
Severity score for the disordered items of the course of thought of the SPI-A
SPI-A:Schizophrenia Proneness Instrument
Time frame: day 1
Severity score for speech disorganization and formal thought disorders on the TLC Scale
TLC: Thinking, Language and Communication Rating Scale
Time frame: day 1
Neuropsychological rating scales scores (CVLT)
CVLT (California Verbal Learning test) (quantitative variable): CVLT: number of correct recognitions
Time frame: day 1
Neuropsychological rating scales scores (CVLT total)
CVLT (California Verbal Learning test) (quantitative variable): CVLT total: total number of words recalled during the test Recognition
Time frame: day 1
Neuropsychological rating scales scores (Front and back spans)
Front and back spans (quantitative variable) Front span size (number of digits recalled in front order)
Time frame: day 1
Neuropsychological rating scales scores (Front and back spans 2)
Front and back spans (quantitative variable) Reverse span size (number of digits recalled in reverse order)
Time frame: day 1
Neuropsychological rating scales scores (TAP 1)
TAP- Working Memory :Number of omissions TAP(Test of Attentional Performance) (quantitative variable)
Time frame: day 1
Neuropsychological rating scales scores (TAP 2)
TAP- Sustained attention :Number of omissions TAP(Test of Attentional Performance) (quantitative variable)
Time frame: day 1
Neuropsychological rating scales scores (TAP 3)
TAP- Flexibility :Number of errors TAP(Test of Attentional Performance) (quantitative variable)
Time frame: day 1
Neuropsychological rating scales scores (TAP 4)
TAP- Incompatibility TAP(Test of Attentional Performance) (quantitative variable)
Time frame: day 1
Neuropsychological rating scales scores (TAP 5)
TAP- Divided attention
Time frame: day 1
Cannabis Abuse Screening Test (CAST) score
CAST: Cannabis Abuse Screening Test
Time frame: day 1
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