Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Study of MBX 1416 in Healthy Subjects

Part A/B/C Inclusion Criteria: 1. Female and male adults, ages ≥ 18 and ≤ 65 years with a body mass index (BMI) ≥ 18 kg/m² to ≤ 30.0 kg/m² and fasting glucose \< 100 mg/dL and HbA1c \< 5.7%. 2. Female subjects of childbearing potential (WOCBP) and male subjects must use highly effective contraception. Part A/B/C Exclusion Criteria: 1. Pregnant, lactating or intending to become pregnant during the study. 2. Use of weight-lowering pharmacotherapy or participation in a clinical weight control study within the previous 3 months prior to the first dose of study drug. 3. Presence of clinically significant ECG findings 4. Subjects with a prior history of any serious adverse reaction, hypersensitivity or angioedema to GLP-1 receptor agonists, study drug or drug components. 5. Abnormal laboratory results at Screening. 6. History of renal disease or abnormal kidney function tests at Screening 7. Presence of any clinically significant physical exam, ECG, or laboratory findings at screening.