Protocols for the community-based management of acute malnutrition (CMAM) have not changed significantly for more than 20 years, with relatively complex treatment protocols and persistent supply chain challenges that have limited overall program coverage, leaving millions of malnourished children without care annually. The overarching goal of this research project is to simultaneously test two novel simplified approaches in CMAM with potential to improve program coverage. The simplified approach includes two parallel clinical trials for SAM and MAM treatment. For the Family MUAC follow-up study, children who recover from these two parallel clinical trials will be enrolled in trial to test the effectiveness of MUAC screening at home by the child's caregivers as a self-referral strategy, compared to a scheduled health facility-led strategy and the standard of care of community-based follow-up visits.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
DIAGNOSTIC
Masking
DOUBLE
Enrollment
3,600
nutrition, IYCF, WASH education
anthropometric screening by health care workers at 1, 3, and 6 months
family MUAC training for the primary caregiver present at the time of recovery
Sekota
Sekota, Amhara, Ethiopia
NOT_YET_RECRUITINGTeltele
Teltelē, Oromiya, Ethiopia
RECRUITINGGode
Gode, Somali, Ethiopia
RECRUITINGnumber of episodes of relapse to acute malnutrition identified
Time frame: 6 months
weight-for-height Z-score (WHZ) at time relapse to acute malnutrition identified
Time frame: 6 months
mid-upper arm circumference (MUAC) at time relapse to acute malnutrition identified
Time frame: 6 months
number of episodes of relapse to edematous malnutrition / kwashiorkor identified
Time frame: 6 months
recovery rates following treatment of relapse to acute malnutrition
Time frame: 6 months
mortality
Time frame: 6 months
hospitalization
Time frame: 6 months
loss to follow-up
Time frame: 6 months
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