Distinct Metastatic Phenotypes Between Early-onset and Late-onset Colorectal Cancer

Inclusion Criteria: * The initial diagnosis of colonoscopy and pathology belongs to colorectal cancer; * Patients should sign an informed consent form after fully understanding the purpose, procedures and potential risks of the study, indicating their voluntary participation in the research. Exclusion Criteria: * Patients with obvious local or systemic severe infection; * Acute abdomen: intestinal obstruction, peritonitis, intestinal perforation; * Have a systemic underlying disease that has not been controlled, or is unstable; * Patients with poor physical fitness or serious other organic diseases who cannot tolerate anesthesia and surgery; * Women during pregnancy, perinatal and lactation; * Patients with severe mental disorders (such as schizophrenia, bipolar disorder, etc.) or patients who are mentally incapable or unable to understand the requirements for participation in the study.