The purpose of this study is to evaluate the efficacy of an intravenous (IV) perioperative dexamethasone regime in the clinical outcomes after a robotic-assisted Total Knee Arthroplasty (TKA) in a Hispanic population. The study aims to propose an alternative to opioid-based pain treatment following TKA. The study hopefully validates the use of a two-dose, 8mg intravenous dexamethasone regimen for improving pain and range of motion scores in patients undergoing primary, unilateral TKA for osteoarthritis. One dose will be applied prior to incision and the other at post-operative day (POD) 1.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
100
Two 8 mg doses. One dose applied prior to incision and the other at POD1
Morphine 0.1 mg per kg intravenous every 6 hours
2 tabs of oral oxycodone combined with acetaminophen every 6 hours (the same pill includes both drugs)
University of Puerto Ric-Dr. Federico Trilla Hospital
Carolina, Puerto Rico
POD 1 Visual Analogue Scale Pain Scores
Range: 0-10 (10 indicates highest degree of pain)
Time frame: Measured at 7:00AM day after surgery
POD 2 Visual Analogue Scale Pain Scores
Range: 0-10 (10 indicates highest degree of pain)
Time frame: Measured at 7:00AM two days after surgery
POD 3 Visual Analogue Scale Pain Scores
Range: 0-10 (10 indicates highest degree of pain)
Time frame: Measured at 7:00AM three days after surgery
POD 1 Range of Motion
Time frame: Measured at 7:00AM the day after surgery
POD 2 Range of Motion
Time frame: Measured at 7:00AM two days after surgery
POD 3 Range of Motion
Time frame: Measured at 7:00AM three days after surgery
Daily Dextrose Concentration (mg/dL)
Time frame: Measured at 7:00AM for 3 days after surgery
Length of Stay
Measured in days
Time frame: From hospital admission to the date of discharge (About 3 days)
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.