The research endeavors to examine the critical composition of Polyunsaturated Fatty Acids (PUFAs) in premature infants across different gestational stages and under varying disease conditions, and delineate the metabolic attributes of PUFAs in premature infants and their interplay with the onset of diseases. This study anticipates furnishing a theoretical foundation for the rationalization of PUFAs supplementation in premature infants and for informing strategies related to disease prevention and management.
Study Type
OBSERVATIONAL
Enrollment
600
Mortality and severe complications of premature infants
incidence of death，NEC，PDA，BPD，IVH，PVL and sepsis
Time frame: before discharge
Mortality
death
Time frame: before discharge
NEC
Bell stage II or III
Time frame: before discharge
PDA
confirmed by echocardiography
Time frame: before discharge
BPD
nasal CPAP/NIPPV or invasive ventilation requirement at 36 weeks postmenstrual age or at discharge, transfer or death if before 36 weeks
Time frame: before discharge
IVH
Papile grades 3-4
Time frame: before discharge
PVL
periventricular cysts on cranial ultrasound or magnetic resonance imaging
Time frame: before discharge
sepsis
blood culture positive
Time frame: before discharge
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