Surface Mechanomyography Using a Parasternal Patch to Measure and Detect Respiratory Drive and Effort

University Hospital, Angers10 enrolled

Overview

Surface mechanomyography (sMMG) has been proposed as a tool to study muscle mechanical activity. sMMG is a noninvasive technique using specific transducers to record muscle surface oscillations due to mechanical activity of the motor units . It could be of major interest for the detection of respiratory efforts in patients with respiratory failure. This study aims at assessing the performances of sMMG to measure and detect respiratory drive and effort in healthy volunteers.

Study Type

INTERVENTIONAL

Allocation

Purpose

DEVICE_FEASIBILITY

Masking

SINGLE

Enrollment

Conditions

Acute Respiratory Failure

Interventions

non-invasive ventilation with or without resistanceDEVICE

non-invasive ventilation with or without resistance.

Eligibility

Sex: ALLMin age: 18 YearsMax age: 60 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * healthy volunteer * Age \> 18 and \< 60 * Informed consent * Fasting * Subjects covered by or having the rights to medical care assurance Exclusion Criteria: * Obesity (BMI \> 30 kg.m-2) * Respiratory disease * Cardiovascular disease * Contraindication to the insertion of a nasogastric tube * Incapacity to consent * Pregnancy, breastfeeding * Bad understanding of the French language, * Other protected person according to articles L1121.7 and L1121.8 of the French Public Health Act.

Locations (1)

Angers University Hospital

Angers, France

Outcomes

Primary Outcomes

Accuracy of sMMG to detect respiratory effort

Delays between the beginning of the respiratory effort detected by sMMG and Eadi and the end of the respiratory effort detected by sMMG and Eadi (msec)