The purpose of this study is to prove whether a fluoride/zinc lactate containing mouthrinse is able to reduce dental plaque and gingival inflammation in patients who have gingivitis when applied twice daily during brushing at home over a period of 12 weeks.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
90
Amine/zinc lactate/fluoride system (250 ppm F), meridol®, Colgate-Palmolive
Sodium fluoride mouthwash 250 ppm
Technische Universität Dresden
Dresden, Germany
Whole-mouth Mean Modified Gingival Index (MGI)
Gingivitis, gingival severity and gingival, interproximal scores as measured by the Gingival Index as difference from baseline to 24 weeks between the study groups.
Time frame: Baseline, 3 weeks, 12 weeks, 24 weeks
Turesky Modification of the Quigley Hein Plaque Index (PI)
Plaque, plaque severity and plaque interproximal scores as measured by the Plaque Index as difference from baseline to 24 weeks between the study groups and at each time-point.
Time frame: Baseline, 3 weeks, 12 weeks, 24 weeks
Intraoral scans
Quantitative changes \& before/after imagery from intraoral scans
Time frame: Baseline, 3 weeks, 12 weeks, 24 weeks
Patient-reported experiences
Changes in participant-reported experience as determined through participant-questionnaire
Time frame: Baseline, 3 weeks, 12 weeks, 24 weeks
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