Cefepime and Unictam on Preventing Post-Cesarean Surgical Site Infections

Beni-Suef University213 enrolled

Overview

the aim of this study is to evaluate the efficacy of employing cefepime (CFM) versus ampicillin/sulbactam (AMS) in lowering the rate of post-cesarean surgical site infections.

A prospective randomized clinical study conducted in the department of obstetrics and gynecology of Beni-Suef University Hospital . A total of 213 women were assessed for eligibility, 13 of which were excluded. A total of 200 pregnant women who were eligible for elective cesarean sections (CS). The overall median duration of postoperative followed up was from 10 days to one month to determine the surgical site infection (SSI).

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

SINGLE

Enrollment

213

Conditions

Cesarean Section; Infection

Interventions

Cefepime 1000 MGDRUG

Cefepime is a fourth-generation cephalosporin antibiotic

Ampicillin-sulbactamDRUG

Broad-Spectrum Antibiotic

Eligibility

Sex: FEMALEMin age: 18 YearsMax age: 40 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Pregnant women within age group more than18 years. * Pregnant women with elective cesarean delivery. * Previous and primary cesarean delivery. Exclusion Criteria: Severe hepatic disease women Emergent cesarean deliveries. Women with medical disorders as pre-gestational diabetes, anemia, hypertension, or preeclampsia. Women who had a skin infection adjacent to the operative site.

Locations (1)

Beni-suef university Hospital

Banī Suwayf, Beni Suweif Governorate, Egypt

Outcomes

Primary Outcomes

surgical site infection

pain, redness, swelling, warm skin around the wound, yellow or green discharge

Time frame: 1 month

Data from ClinicalTrials.gov

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