It is a single-center randomized controlled trial that aims to figure out the effect of the hypotension prediction index (HPI) on the prevention of acute kidney injury (AKI) after robot-assisted urological surgery. The primary hypothesis is that HPI software guidance prevents postoperative AKI by reducing the duration and severity of intraoperative hypotension (IOH).
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
SINGLE
Enrollment
124
The hemodynamic condition of the HPI group will be managed by HPI guidance which is derived by arterial pressure waveform information, including Eadyn, SVV, dP/dt.
Ewha Womans University Mokdong Hospital
Seoul, Seoul, South Korea
Acute kidney injury
Occurrence of acute kidney injury after robotic urological surgery
Time frame: Seven day after the operation
Depth and duration of hypotension
Depth and duration of hypotension will be assessed by calculating time weighted average (TWA) of hypotension under mean arterial pressure under 65 mmHg during the operation
Time frame: From applying HPI (hypotension prediction index) monitor to the arterial line to the end of the anesthesia
Hypotension prediction index
Time weighted average of hypotension prediction index during the operation
Time frame: From applying HPI (hypotension prediction index) monitor to the arterial line to the end of the anesthesia
Biomarkers
Biomarkers for early detection of AKI - Cystacin C, KIM-1
Time frame: Baseline, immediate postop
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