Assessing Lung Dynamics and Respiratory Functions in Minimal Flow Anesthesia: A Prospective Study

Ataturk University60 enrolled

Overview

The patients were randomized into two groups medium flow anesthesia (MeFA) and minimal flow anesthesia (MiFA). While MeFA received medium flow anesthesia with 2 lt/min, MiFA received minimal flow anesthesia with 0.5 lt/min fresh gas flow. In both groups dynamic compliance values, peak inspiratory pressure (PIP) values, total inhalation anesthetic drug consumption, total remifentanil drug consumption, duration of anesthesia, and duration of surgery were recorded. The FVC, FEV1, and FEV1/FVC values of the patients in both groups were evaluated and noted 24 hours before the operation, after the operation 2nd, 8th, and 24th hours.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

SCREENING

Masking

SINGLE

Enrollment

Conditions

Medium Flow Anesthesia Minimal Flow Anesthesia Pulmonary Function Test Compliance, Patient

Interventions

Medium flow anesthesiaOTHER

Group MeFA; after reaching the MAC 1 value with 4lt/min 50% O2 - 50% air and 8% desflurane with remifentanil infusion, medium flow anesthesia was started with 2 lt/min 50% O2 - 50% air with MAC 1 concentration desflurane. The vaporizer was closed at the end of the last suture, and the flow was increased to 80% oxygen at 6 lt/min.

Minimal flow anesthesiaOTHER

Group MiFA; after reaching the MAC 1 value with 4 lt/min 50% O2 - 50% air and 8% desflurane with remifentanil infusion, minimal flow anesthesia was started with 0.50 lt/min 50% O2 - 50% air with MAC 1 concentration of desflurane. The vaporizer was closed at the end of the last suture, and the flow was increased to 80% oxygen at 6 lt/min.

Eligibility

Sex: ALLMin age: 18 YearsMax age: 65 Years

Medical Language ↔ Plain English

Inclusion Criteria: * ASA I-II * 18-65 years of age, who will undergo elective laparoscopic cholecystectomy surgery Exclusion Criteria: * ASA III-IV * Smokers * Body mass index (BMI) \> 40 kg / m2, * Patients with cardiovascular system disease * Chronic respiratory diseases, * Patients whose pulmonary function tests cannot be applied and who have problems with pulmonary function tests during the examination of the chest disease consultant

Locations (1)

Erkan Cem ÇELİK

Erzurum, Turkey (Türkiye)

Outcomes

Primary Outcomes

Dynamic Compliance assessment

Dynamic Compliance will be assessed 5th minutes after endotracheal intubation

Time frame: 5th minutes after endotracheal intubation

Dynamic Compliance assessment

Dynamic Compliance will be assessed 5th minutes after the surgical incision

Time frame: 5th minutes after surgical incision

Dynamic Compliance assessment

Dynamic Compliance will be assessed 10th minutes after the surgical incision

Time frame: 10th minutes after surgical incision

Dynamic Compliance assessment

Dynamic Compliance will be assessed 30th minutes after the surgical incision

Time frame: 30th minutes after surgical incision

Dynamic Compliance assessment

Dynamic Compliance will be assessed 60th minutes after the surgical incision

Time frame: 60th minutes after surgical incision

Dynamic Compliance assessment

Dynamic Compliance will be assessed immediately after the end of the surgical suturing

Time frame: immediately after the end of the surgical suturing