The main purpose of this study is to find out whether taking part in a group-based interpersonal psychotherapy (IPT) program designed to improve mood and lessen stress in girls with PCOS will improve depression, unhealthy eating behaviors, weight, and insulin resistance.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
30
IPT group-virtual
Children's Hospital Colorado
Aurora, Colorado, United States
Center for Epidemiologic Studies-Depression Scale
Depression symptoms will be assessed by the Center for Epidemiologic Studies-Depression Scale. Scores range from 1 to 4. The scoring of positive items is reversed. Possible range of scores is zero to 60, with the higher scores indicating the presence of more symptomatology.
Time frame: Baseline
Center for Epidemiologic Studies-Depression Scale
Depression symptoms will be assessed by the Center for Epidemiologic Studies-Depression Scale. Scores range from 1 to 4. The scoring of positive items is reversed. Possible range of scores is zero to 60, with the higher scores indicating the presence of more symptomatology.
Time frame: 6-Week Follow-Up Assessment
Center for Epidemiologic Studies-Depression Scale
Depression symptoms will be assessed by the Center for Epidemiologic Studies-Depression Scale. Scores range from 1 to 4. The scoring of positive items is reversed. Possible range of scores is zero to 60, with the higher scores indicating the presence of more symptomatology.
Time frame: 6-Month Follow-Up Assessment
Emotional Eating Scale Adapted for Children
Disordered eating will be assessed by the Emotional Eating Scale Adapted for Children. The scale has been adapted for children and assesses eating in response to negative affect, such as feeling sad or irritated. The scale ranges from "I have no desire to eat" to "I have a very strong desire to eat" and averages how many days a week the participant eats based on that feeling.
Time frame: Baseline, 6-Week Follow-Up Assessment, 6-Month Follow-Up Assessment
Loss-of-Control Eating Disorder Questionnaire
Loss-of-control eating will be assessed via the 19-item Loss-of-Control Eating Disorder Questionnaire (LOC-ED-Q), which shows sound psychometric properties in adolescents using Yes/No.
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Time frame: Baseline, 6-Week Follow-Up Assessment, 6-Month Follow-Up Assessment
Reward Based Eating Drive Scale
Reward based eating will be assessed by the Reward Based Eating Drive Scale. This is a self-report questionnaire which assesses reward-based eating that shows sound psychometric properties. The total score is summed at the end; a higher total is indicative of reward-based eating.
Time frame: Baseline, 6-Week Follow-Up Assessment, 6-Month Follow-Up Assessment
BMI
Fasting BMI (kg/m2) will be derived from measured height in triplicate by stadiometer and measured fasting weight by calibrated digital scale. BMI z-score and BMI %ile will be computed to determine eligibility (BMI ≥75th percentile).
Time frame: Baseline, 6-Week Follow-Up Assessment, 6-Month Follow-Up Assessment
Insulin Resistance
Blood will be sampled via a venipuncture procedure following a 10-hour overnight fast to measure fasting insulin. Insulin resistance will be estimated from fasting insulin and glucose with the homeostatic model assessment of insulin resistance (HOMA-IR).
Time frame: Baseline, 6-Week Follow-Up Assessment, 6-Month Follow-Up Assessment
Dysglycemia
Blood will be sampled via a venipuncture procedure following a 10-hour overnight fast to measure fasting insulin. Insulin resistance will be estimated from fasting insulin and glucose with the homeostatic model assessment of insulin resistance (HOMA-IR).
Time frame: Baseline, 6-Week Follow-Up Assessment, 6-Month Follow-Up Assessment
Dyslipidemia
Blood will be sampled via a venipuncture procedure following a 10-hour overnight fast to measure dyslipidemia. Insulin resistance will be estimated from fasting insulin and glucose with the homeostatic model assessment of insulin resistance (HOMA-IR).
Time frame: Baseline, 6-Week Follow-Up Assessment, 6-Month Follow-Up Assessment