Effect of Hyoscine- Bromide on Duration of the First Stage of Labor

Ain Shams University60 enrolled

Overview

Spasmolytic drugs are frequently used in delivery rooms to overcome cervical spasms and thus reduce the duration of labor. The aim of this randomized double blind placebo controlled trial is to study the efficacy of hyoscine butylbromide (HBB) for shortening of the first stage of labor in primigravid women.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

QUADRUPLE

Enrollment

Conditions

Labor

Interventions

hyoscine butylbromideDRUG

will be given during first stage of labor intravenously

normal salineOTHER

placebo

Eligibility

Sex: FEMALEMin age: 20 YearsMax age: 40 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: 1. Primigravid women. 2. Singleton pregnancy. 3. Presenting by the vertex. 4. Gestational age between 37 and 42 weeks 5. In active phase of labor with a cervical dilatation between 4-5 cm, with either intact membranes or spontaneous rupture of membranes for less than 12 h Exclusion Criteria: 1. Previous uterine scarring. 2. Malpresentation. 3. Antepartum hemorrhage. 4. Labor induction 5. Contraindication to vaginal delivery. 6. Contraindication to hyoscine.

Locations (1)

Ain Shams University maternity hospital

Cairo, Cairo/القاهرة, Egypt

RECRUITING

Outcomes

Primary Outcomes

duration of first stage of labor

duration

Time frame: 6 months

Central Contacts

Maii Nawara, MD

CONTACT

+201001848388 maii_nawara@hotmail.com

Data from ClinicalTrials.gov

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