To study the current status of cardiotoxicity of arsenious acid by analyzing the literature, monitoring data, and real-world applications, and to discuss risk factors and preventive and control measures.
Through the project study, the risk rate of cardiotoxicity caused by arsenious acid will be verified and evaluated, and a typical case analysis will be conducted to assess the risk and benefit ratio of clinical use of arsenious acid injection and to formulate preventive measures, so as to guide the holder of the marketing authorization to carry out in-depth safety studies and to ensure the public's safe use of the drug.
Study Type
OBSERVATIONAL
Enrollment
400
Patient use of arsenite sodium chloride injection
China
Jinan, Shandong, China
RECRUITINGFirst Affiliated Hospital of Shandong First Medical University ( Qianfoshan Hospital of Shandong Province )
Jinan, Shandong, China
RECRUITINGarrhythmia
Electrocardiogram shows arrhythmia with marked QT prolongation
Time frame: through study completion, an average of 1 year
adverse reaction
All cardiac-related adverse events in the course of the disease regimen
Time frame: through study completion, an average of 1 year
troponin
Troponin values
Time frame: through study completion, an average of 1 year
Echocardiogram LVEF
Echocardiogram LVEF values
Time frame: through study completion, an average of 1 year
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