Effect of Indoor Plants on Cardiopulmonary System

Lina Zhang41 enrolled

Overview

This is a randomized controlled human exposure crossover study, aims to explore the health benefits of indoor plants on cardiopulmonary system on adults.

The researchers will conduct a randomized cross-controlled trial involving 48 healthy adults in Hangzhou, China. These participants will be randomly assigned into two groups, each comprising 24 individuals. Each participant will undergo two separate exposures in an office setting: one exposure without any plants present, and another exposure with 34 to 38 potted plants. A washout period of at least 4 weeks will be implemented between the two exposures. Questionnaires, physical examinations and the collection of biological samples will be conducted prior to exposure and after exposure. In addition, the monitoring of negative air ion, air pollutants and noise exposure, as well as collection of environmental microbial samples, will be conducted on weekdays. Researchers will gather samples of blood, urine, nasal secretion, and exhaled breath condensate from participants.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

SINGLE

Enrollment

Conditions

Cardiopulmonary

Interventions

Plants placed in an office environmentOTHER

The intervention group will be provided with an intervention consisting of 34-38 potted plants arranged in an office environment for a duration of 8 hours (09:00-17:00) on weekdays (Monday to Friday) for 4 weeks.

Devoid of any plant presence in an office environmentOTHER

Participants assigned to the control group will be exposed to an office environment devoid of any plant presence for a duration of 8 hours (09:00-17:00) on weekdays (Monday to Friday) for 4 weeks.

Eligibility

Sex: ALLMin age: 18 YearsMax age: 35 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Living in Hangzhou during the study period; * Non-smoking, no history of alcohol or drug abuse; * Staying indoors in daytime we required. Exclusion Criteria: * Current or ever smokers; * Subjects with allergic disease, such as allergic rhinitis, allergic asthma, and atopy; * Subjects with cardiovascular disease, such as congenital heart disease, pulmonary heart disease, and hypertension; * Subjects with respiratory disease, such as asthma, chronic bronchitis, and chronic obstructive pulmonary disease; * Subjects with chronic disease, such as diabetes, chronic hepatitis, and kidney disease; * Subjects with a history of major surgery; * Medication use or dietary supplements intake in recent two months; * Unable to cooperate with follow-up.

Locations (1)

Zhejiang Chinese Medicine University

Huangzhou, Zhejiang, China

Outcomes

Primary Outcomes

Forced Vital Capacity(FVC)

We plan to measure forced vital capacity (FVC) of lung function.

Time frame: Baseline and after 4 weeks plants exposure in first stage, and after washout period, baseline and after 4 weeks plants exposure in second stage.

Secondary Outcomes

Blood Pressure(BP)

We plan to measure systolic blood pressure (SBP) and diastolic blood pressure (DBP).

Time frame: Baseline and after 4 weeks plants exposure in first stage, and after washout period, baseline and after 4 weeks plants exposure in second stage.

Heart Rate Variability(HRV)

We plan to measure Heart Rate Variability (HRV).

Time frame: Baseline and after 4 weeks plants exposure in first stage, and after washout period, baseline and after 4 weeks plants exposure in second stage.

Data from ClinicalTrials.gov

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