This prospective, observational study is a single center clinical registry of patients referred for management of symptomatic or asymptomatic Premature Ventricular Contractions (PVCs). Subjects will be followed through 12 months. The study will enroll approximately 50 patients.
This study is intended to monitor patients presenting with Premature Ventricular Contractions (PVCs) and ventricular arrhythmias using implantable loop recorders (ILRs) from the time of their initial presentation of PVCs to assess for the incidence of all cardiac arrhythmias detected with long term monitoring in this population. It is also intended to evaluate for clinical, biomarker and radiological evidence of myocarditis in this cohort to understand association with incident arrhythmias and understand the role of implantable loop recorders (ILRs)in managing these patients.
Study Type
OBSERVATIONAL
Enrollment
50
Patients presenting with PVCs and ventricular arrhythmias will be monitored using ILRs from the time of their initial presentation of PVCs to assess for the incidence of all cardiac arrhythmias. They will also be evaluated for clinical, biomarker and radiological evidence of myocarditis to understand association with incident arrhythmias.
Kansas City Heart Rhythm Institute - Roe Clinic
Overland Park, Kansas, United States
RECRUITINGOverland Park Regional Medical Center
Overland Park, Kansas, United States
RECRUITINGCenterpoint Medical Center Clinic
Independence, Missouri, United States
Identification of unrecognized myocarditis
Identification of unrecognized myocarditis in patients presenting PVCs with positive FDG-PET \[fluorodeoxyglucose (FDG)-positron emission tomography (PET)\] scanning.
Time frame: 12 Months
Evaluation of efficacy of immunosuppressive therapy - PVC burden reduce
Evaluation of efficacy of immunosuppressive therapy in patients with NICM with PVCs in reducing PVC burden as compared to their baseline PVC burden.
Time frame: 12 Months
Evaluation of efficacy of immunosuppressive therapy - LVEF improvement
Evaluation of efficacy of immunosuppressive therapy in patients with NICM by documenting improvement in LVEF compared to their baseline LVEF.
Time frame: 12 Months
Associated atrial and ventricular arrhythmias
Assessing incidence of associated atrial and ventricular arrhythmias as detected with ILR recordings in patients with apparently idiopathic PVCs.
Time frame: 12 Months
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Centerpoint Medical Center
Independence, Missouri, United States
RECRUITINGResearch Medical Center Clinic
Kansas City, Missouri, United States
RECRUITINGResearch Medical Center
Kansas City, Missouri, United States
RECRUITING