Comparison of Hemodynamic Changes With Morphine Versus Esmolol During Induction of Anaesthesia

Pakistan Navy Station Shifa Hospital110 enrolled

Overview

Comparing hemodynamic changes with morphine versus esmolol as an adjuvant agent during induction of Anaesthesia

Comparing hemodynamic profile of patients during induction of General Anesthesia with intravenous morphine as an adjuvant drug versus Intravenous esmolol as an adjuvant agent,My aim is to study which drug has superior hemodynamic profile in terms of hemodynamic stability of patient requiring General Anesthesia.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

SUPPORTIVE_CARE

Masking

NONE

Enrollment

110

Conditions

Intubation Complication

Interventions

Intravenous morphineDRUG

Morphine group(an opioid), participants were given intravenous morphine(an opioid) at induction of General Anaesthesia before laryngoscopy and intubation. The other group,Esmolol group(cardioselective beta blocker), participants were given intravenous esmolol(cardioselective beta blocker) during induction of General Anesthesia before laryngoscopy and intubation.

Eligibility

Sex: ALLMin age: 25 YearsMax age: 55 Years

Medical Language ↔ Plain English

Inclusion Criteria: * ASA 2 patients presenting for elective surgery. Exclusion Criteria: * Patients having major cardiac disease. * Metastatic disease. * Pregnant females. * Those unwilling to be part of study.

Locations (1)

PNS Shifa Hospital

Karachi, Sindh, Pakistan

Outcomes

Primary Outcomes

Blood pressure

Change in blood pressure between baseline value and post Intubation value will be measured in millimeter of mercury (mmHg).

Time frame: 06 months

Pulse rate

Change in pulse rate between baseline value and post intubation value will be measured per minute.

Time frame: 06 months

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.