The purpose of the project is to investigate exercise performance in humans following bronchodilation induced by acute inhalation of beta2-agonist indacaterol + mometasonefuroate
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
QUADRUPLE
Enrollment
30
Participants are administered 125 µg indacaterol + mometasonefluroate
Participants are administered placebo
Participants are administered 500 µg indacaterol + mometasonefluroate
August Krogh Building
Copenhagen, Denmark
RECRUITINGPower output during sprint testing
Power output measured in Watts during a sprint on a bike ergometer
Time frame: Through study completion, an average of 3 weeks
Power output during time trial
Mean power output measured in Watts during a time trial on a bike ergometer
Time frame: Through study completion, an average of 3 weeks
Forced Expiratory Volume in 1 second (FEV1)
FEV1 measured by spirometry
Time frame: Through study completion, an average of 3 weeks
Quadriceps strength
Maximal torque (Nm) achieved during isometric contraction
Time frame: Through study completion, an average of 3 weeks
Respiratory muscle function
Mouth inspiratory and expiratory pressures (MD Diagnostics, RP-check, handheld respiratory pressure meter)
Time frame: Through study completion, an average of 3 weeks
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